The Significance of C-Reactive Protein in Adult Obese and Centrally Obese Group

Abstract

Objective: To see the significance of C-reactive protein in adult obese and centrally obese groups

Study Design: Descriptive Study

Place and Duration of Study: This study was carried out from free camp for obesity in Clifton area and Punjab Colony, Karachi from November 2010 to April 2011.

Subjects & Methods:  Overweight adults (20-40 years) were selected along with the history of Xanthomas, yellow coloration of eyes, and high blood pressure and cardiac arrest.100 samples were taken for lipid profile, and C-reactive protein (CRP). The Body Mass Index (BMI) and waist hip ratio was measured by following the criteria of the National Heart Lung And Blood Institute.

Results: Hundred patients were selected for the purposes of study. These patients were divided into two categories i.e. adult obese and centrally obese. Body mass index (BMI) was increases (M=31.27±1.2, F= 31.3±0.27) in both sexes of adult, whereas waist hip ratio was slightly increases in adult male (1.22 ±0.04) as compared to female (1.14±0.025). In comparison of centrally obese male and female, body mass index was high in females (34.1±0.67) as compared to male (31.68±0.53), but waist hip ratio was elevated in male cases (2.16±0.14) than female (2.16±0.14), when compared with control cases. Whereas C-reactive protein was high in female cases (27.8± 1.20) as compared to male (24.20± 0.86). In case of centrally obese, markedly increased level was observed in female (30.63± 2.57) as compared with male (28.9±2.35).

Conclusion: There is significant effect of inflammatory marker C-reactive protein in both male and female obese and centrally obese adult groups.