To Study the Role of Serum Biliurbin and Lipoproteins in Prediction of Ischemic Heart Disease

Abstract

Background: An inverse relationship between the bilirubin level and ischaemic heart disease was accounted.

Study Design: Cross Sectional Study.

Place and Duration of Study: This study was conducted at Dept. of Biochemistry, Fatima Jinnah Medical College, Lahore from Feb. 2007 to July 2007.

Materials and Methods: Study was performed to determine if serum bilirubin, when combined with various risk factors like lipid and lipoprotein predict ischemic heart disease (IHD).

Results: It is observed that the bilirubin is negatively correlated with hemoglobin, albumin, HDL and LDL-cholesterol. On the other hand a direct correlation with total lipid, cholesterol and ratio of cholesterol/HDL-cholesterol is also observed. High level of serum creatinine level was also found in the patients as compared to normal subject.

Conclusion: Our study observed not a definite relationship between serum bilirubin and IHD. Hence the relationships between bilirubin and lipoproteins (risk factors of IHD) require further clarification, although abnormal intermediary metabolism and antioxidant deficiency may be possible linking factors.