Role of Testosterone in Male Fertility/ Infertility in Tertiary Care Hospital of Karachi

Abstract

Study Design: Case Control study. 
Place and Duration of Study: This study was conducted at the Gynecology and Obstetrics Department, Jinnah Post 
Graduate Medical Center Karachi from October 2016 to May 2018.  
Materials and Methods: This study was conducted on 100 married males in collaboration with RHS centre (Male 
infertility clinic) at JPMC, Karachi. The male patients were divided into two major groups Group A (control group 
of fertile males) and Group B (case group of infertile males), Group B is further subdivided into three subgroups of 
Azoospermia, Oligospermia and Others causes of infertility. Semen Analysis was done following WHO criteria and 
the Quantitative measurement of testosterone in the serum was carried out by ELISA kit. 
Results: The serum levels of testosterone was found out to be lower in infertile male group B1 (Azoospermia) and 
higher in group B2 (Oligospermia) and remains normal in Group A (Proven fathers) and Group B3 (Others). 
Conclusion: Testosterone is lower in Azoospermia, Normal in Proven Fathers and higher in Oligospermia patient.