Frequency of Malignancy in Goiter in Pakistan: A Review of 359 Thyroidectomics

Abstract

Objective: To determine the frequency of malignancy in patients presenting with goiter undergoing for surgery. 
Study Design:  An observational study. 
Place and Duration of Study: Surgical Department of Social Security Hospital Islamabad January 2002 to 
February 2011. 
Patients and Methods: All patients more than 10 years of age underwent thyroidectomy were included in the study. 
Postoperatively histopathologies of specimens were evaluated in all patients. 
Results: A total of 359 patients were operated and post operative histopathology specimens were reviewed. Eleven 
patients (3.06%) were having carcinoma. . Among all the thyroid carcinomas, papillary carcinoma was the 
commonest i.e. (45.45%, 5/11) followed by follicular carcinoma (27.27%, 3/11). Anaplastic carcinoma was seen in 
(18.18%, 2/11) and medullary carcinoma seen only in (9.09%, 1/11) 
Conclusion: Thyroid carcinoma is not an uncommon condition. Frequency of papillary carcinoma is very high in 
females among all the thyroid carcinoma