High Incidence of Dyslipidemia In Obese Type 2 Diabetics

Abstract

Objective: To ascertain the effect of Body Mass Index (BMI) on plasma lipid profile in type 2 diabetes  
mellitus (T2DM).  
Study design: Comparative, observational study 
Place and duration of study: Army Medical College, Rawalpindi from Jan 2007- June 2010. 
Patients and Methods: Sample size was 60, subdivided in to two groups. Group 1 comprising on 30 type 2 
diabetics with BMI < 25, whereas Group 2 consisted of 30 type 2 diabetics with BMI > 28. Blood glucose, HbA1c, 
plasma cholesterol and triglyceride levels were determined.  
Results: Group 1 consisted of 56% males and 44 % females, whereas Group 2 had 54 % males and 46 % females. 
Mean age to develop T2DM for group 1 was 44.60 + 1.22 years and for group 2 was 42.13 + 0.86 years. BMI of 
group 1 was 20.29 + 0.56 and Group 2 was 28.95 + 0.26. Mean plasma cholesterol and plasma triglyceride levels of 
group 2 diabetics were significantly higher (p< 0.001) as compared with group 1 non obese diabetics. Whereas, 
mean plasma glucose (p< 0.01) and Glycosylated hemoglobin (p< 0.05) of group 2 diabetics were significantly 
higher as compared with group 1 non obese diabetics 
Conclusion: Dyslipidemia was more marked in obese type 2 diabetics. Whereas diabetics with low BMI had plasma 
lipid profile within normal range.