Anaphylactic Reactions of Ionic and Nonionic Contrasts during Coronary Angiogram

Abstract

Objective: To compare the acute anaphylactic reactions of ionic and nonionic contrasts in patients undergoing 
coronary angiogram. 
Study Design: Experimental Study.  
Place and Duration of Study: This study was conducted in Catheterization Laboratory of Punjab Institute of 
Cardiology, Lahore from 28th September 2007 to 27th March 2008.  
Materials and methods: 200 patients undergoing coronary angiogram, admitted in Punjab Institute of Cardiology 
Lahore through outpatient department (OPD) and emergency ward were included. The socio demographic 
information like name, age sex and address were recorded. After taking informed consent, the patients were divided 
into two groups by using random numbers table before the procedure. First group received ionic and the second 
group received nonionic dye. All patients will undergo coronary angiogram & anaphylactic reactions were recorded. 
Results: Out of 200 patients 153(76.5%) were male and 47(23.5%) were female .Age range was 32-75 yrs with 
mean age of 53.94±10.07 of study population .The study population was divided into two equal groups. First group 
100 patients received Ionic dye while second group100 patients received Non ionic dye .Anaphylactic complications 
during coronary angiogram were more common in patients who received ionic contrast as compared to non ionic 
contrast group. 
Conclusion: Anaphylactic complications during coronary angiogram were more common with ionic dye as 
compared to non ionic contrast.