Comparing the Quality of Life by Using Two Therapeutic Approaches (10% Sulphur Ointment and 5% Permethrin Cream) in Scabies Patients

Abstract

Objective: To compare the quality of life by using two therapeutic approaches (10% sulphur ointment and 5% permethrin cream) in patients with scabies.

Study Design: Retrospective / comparative study.

Place and Duration of Study: This study was conducted in Basic Medical Science Institute and Dermatology Department of Jinnah Postgraduate Medical Centre in Karachi from 1^st Dec 2010 to 30th May 2011.

Materials and Methods: This study sample consisted of 130 (4 dropped out) clinically diagnosed cases of scabies divided into two groups; A and B. Each group was further subdivided into three age groups. Group A was asked to apply 5% permethrin cream on day 0 and to be repeated after 15 days and Group B treated with 10% sulphur ointment for three consecutive nights and repeated on day15. Data was gathered by a questionnaire. Patients follow up was done on days 3, 15 and 30 and quality of life was determined on day 0 and 30 by using Dermatological Life Quality Index.

Results: Quality of life was found to be low in scabies patients and treatment with 10% sulphur ointment and 5% permethrin not only improved clinical symptoms but also their quality of life significantly.

Conclusion: Scabies affects quality of life because of severe itching and lack of sleep and proper topical therapy significantly improves clinical symptoms and quality of life.