Chronic Liver Disease as a Risk Factor for Type 2 Diabetes Mellitus

Abstract

Objectives: To determine the chronic liver disease as the risk factor for Type 2 diabetes mellitus.

Study Design: Cross-sectional study

Place and Duration of Study: This study was conducted at the Medicine Department of Indus Medical College Tando Muhammad Khan from May 2016 October 2016.

Materials and Methods: Patients after diagnosis of chronic liver were included. In the selected cases complete clinical examination routine laboratory investigations were carried out. Cases less than 50 years of the age either gender were selected. Patients with history of obesity, smoking, alcohol consumption, diabetic family history and with history other risk factors of the diabetes were excluded from the study to see the frequency of diabetic mellitus development in the patients with chronic liver disease. Complete data regarding age, gender, residential status, socioeconomic status, virological frequency and glycemic status were noted in the proforma.

Results: Mean age of the patients was 42.12+5.33 years. Male were found in the majority 60.81%. HCV was the most common in 81.08% of the patients. Diabetic mellitus was found in 22.97% of the patients, while 77.3% patients were noted without diagnosis of diabetic mellitus. In this study out of 17 diagnosed cases of type 2 diabetes  mellitus 11 were HCV infected patients and 2 were HBV infected while 2 cases were with coinfection of HBV and HCV.

Conclusion: We concluded that HCV related chronic livers disease is the frequent risk factor for the development of diabetic mellitus.