Spectrum of Thyroid Gland Disorders in Karachi-DDRRL Experience

Abstract

Objective: To find out thespectrum of thyroid gland disorders in association with age and gender  andto identify histological types of thyroid lesions.

Study Design: Descriptive Study.

Place and Duration of Study: This study was carried out at the Department of Histopathology, DOW University (OJHA campus) Karachi from1^stJan 2010 to 31^st Dec 2011.

Materials and Methods: The record of total 208 specimens, were reviewed from the department of Histopathology, DOW University (OJHA campus) Karachi throughout the period from1^stJan 2010 to 31^st Dec 2011. The specimens were received in 10% buffered formalin and processed as per routine laboratory procedure and then embedded in paraffin for block preparation. The sections were stained with the routine haematoxylin and eosin method and were studied and diagnosed by a consultant histopathologist. Difficult cases were discussed in Departmental Consultation Committee.

Results:  Total 208 cases were studied, there was a female predominance 184 (88.5%) and among them majorities were in 3^rd decade of life. Males were 24 (11.5%) commonly seen in 4^th decade of life. The ages ranged from 15-75 years, mean age is 30 years.Nodular hyperplasia was the commonest thyroid lesion found.

Conclusion: The information in the present study may be considered as a baseline data of

thyroid diseases inKarachi and a more elaborate prospective study carried out on a large scale in this country will contribute more to make the things clearer.