Frequency of Renal Derangement in Patients of Asphyxia Neonatorum

Abstract

Objectives:To find the incidence of Renal Derangement in Neonates with Asphyxia Neonatorum.

Study Design:Observational / descriptive study.

Place and Duration of Study:This study was conducted at the Department of Pediatric Medicine, Nishtar Hospital, Multan from January 2016 to January 2017.

Materials and Methods:A total number of 100% (n=264) neonates were included in this study, both genders. SPSS version 23 was used to analyze data, mean ± SD deviation was calculated for numerical variables and frequency (percentages) was calculated for categorical variables. Chi square test was applied to see the effect modification. P value ≤ 0.05 considered as significant.

Results: A total number of 100% (n=264) neonates were included in this study, both gender. Out of these 100% (n=264) patients, 71.6% (n=189) patients having Renal Derangement (creatinine > 0.8 mg/dl). When chi-square was applied to check the effect modification it was observed that gender, stratified Apgar score and stratified birth weight (≤2.5 kg and >2.5 kg) were significantly associated with Renal Derangement with P-values 0.000, 0.05 and 0.000 respectively.

Conclusions:Asphyxia is a major cause of Acute Renal Failure in Neonates, its outcome can be improved with early monitoring of patients renal parameters e.g urea and serum creatinine.