Association Between Leucocytosis and in-Hospital Mortality in Patients Presenting with Acute Ischemic Stroke

Abstract

Objective: To determine the association between leucocytosis and in hospital mortality in patients presenting with acute ischemic stroke.

Study Design: Cohort study

Place and Duration of Study: This study was conducted at the Department of Medicine, Mayo Hospital Lahore from February 2015 to July 2015.

Materials and Methods: Four hundred and sixty patients were included. They were divided in two groups; patients with leucocytosis and patients without leucocytosis. All patients were managed indoor on standard protocol for acute ischemic stroke as per hospital routine and followed-up till discharge. During their stay at hospital, they were monitored on daily basis and, in-hospital mortality was labeled.

Results: The mean age was 49.17±13.58 years with male to female ratio was 2.04:1. Diabetes was found in 71.30% patients, hypertension in 36.5% patients and mortality occurred in 14.57% patients. The OR showed that there is approximately three times more chance of mortality in leucocytosis group as compared to normal WBC group patients i.e. OR=2.92.

Conclusion: There is 2.92 times high chance of in-hospital mortality in leukocytosis as compared to controls in patients presenting with acute ischemic stroke.