Assessment of Lipid Profile Levels in Type – II Diabetes and Non Diabetic Subjects: Attended at Specialized Diabetic Hospital in Karachi

Abstract

Objective: The aim of our study was to assess prevalence and pattern of dyslipidemia in Diabetes and to compare Lipid profile levels between Diabetics and Non-diabetic subjects.

Study Design: Prospective study.

Place and Duration of Study: This study was conducted at the National Institute of Diabetology and Endocrinology (NIDE), Dow University of Health Sciences (DUHS), Karachi, Pakistan from Feb. 2019 to
June 2019.

Materials and Methods: The study included a total of Eighty (80) Type II Diabetes and 80 Non-diabetic subjects with 40 pts. were males and 40 patients were females in both groups. Blood samples were drawn from cases of Diabetes Mellitus (DM) and Non-diabetic controls. All Biophysical parameters and Biochemical tests were done using standard procedures. Values were tabulated for cases and control separately for statistical evaluation.

Results: The total cholesterol (TC), Triglycerides (TG), Very Low Density Lipoprotein (VLDL) and Low Density Lipoprotein cholesterol (LDL) were significantly raised in Diabetics as compared to Non-diabetic subjects; whereas the level of High Density Lipoprotein (HDL) was significantly lower in Diabetic subjects as compared to Non-diabetes.

Conclusion: It was concluded that diabetic patients have high level of Cholesterol, Triglyceride and LDL-C as compared to non-diabetic subjects, whereas the level of HDL-C was significantly low in diabetic patients compared to non-diabetic subjects, thus indicating that diabetic patients were more prone for dyslipidemia, which could cause cardiovascular disorders (CVD)  and its complications.