To Compare the Mean Corneal Endothelial Cell Count Between the Sodium Hyaluronate 1% VS Hydroxy Propyl Methyl Cellulose (HPMC) in Patients Undergoing Phacoemulsification

Abstract

Objective: To determine mean corneal endothelial cell count between the sodiumhyaluronate1% vs. Hydroxy propyl methyl cellulose (HPMC) in patients undergoing phacoemulsification.

Study Design: Randomized control trial (RCT).

Place and Duration of Study: This study was conducted at the Ophthalmology Department, Jinnah Postgraduate Medical Centre; Karachi from 1^st April, 2018 to 30^th   September, 2018.

Materials and Methods: There were 61 patients having cataract were included in this study. Patients were randomly allocated into two groups. Patients in group 1 were treated with sodium hyluronate 1% and group 2 was treated with Hydroxy-propyl-methyl-cellulose 2%. All the patients were underwent phacoemulsification. Foldable intraocular lens (IOL) was implanted in all cases. Measurements of the endothelial cell count were made 1 day before the surgery and at the end of 6 weeks. All the data was entered on the pre-designed proforma.

Results: There were 28(45.2%) male and 34(54.8%) female. Reduction in mean endothelial cell count was significantly high in group 2 as compare to group 1 (p=0.0005).

Conclusion: In conclusion, our study suggests that 2% Hydroxypropyl methylcellulose, compared with sodium hyaluronate 1%, is superior in protecting the corneal endothelial cells.