Microflora of Bile Aspirates and its Antibiogram

Abstract

Objective: To determine the frequency of bacterial infection in patients presenting with Cholelithiasis.

Study Design: Descriptive case-series study.

Place and Duration of Study: This study was carried out in the Surgical Unit Nishtar Hospital, Multan from  October 2007 to September 2008.

Materials and Methods: All adults patients aged 20 years and above who were admitted with a provisional diagnosis of cholelithiasis, over a period of one year were entered into the study. The study included 100 patients between the ages of 20 and 60 years.

Results: The 100 patients who presented with cholelithiasis underwent operation and bile was taken for culture and sensitivity. There were 88 women (88%) and 12 (12%) were men. Age was ranging from 20 to 60 years (mean 44.4 years). 56 (56%) were operated laparoscopically while in 44 (44%) open cholecystectomy was done. Out of 100 bile culture 16 (16%) were positive while in 84 (84%) cases no growth cultured.

Conclusion:.In patients of cholelithiasis bile may be infected and infection may be causative factor in formation of gall stones. Most of the microorganism were sensitive to cefuroxime axetil and ceftrioaxone.