Non-Alcoholic Fatty Liver Disease in Type 2 Diabetes: Effect on Diabetic Control and Lipid Profile

Abstract

Objective: To determine the frequency of non-alcoholic fatty liver disease in patients with type 2 diabetes and to compare the diabetic control and dyslipidemia in diabetic patients with and without non-alcoholic fatty liver disease.

Study Design: Cross sectional study.

Place and Duration of Study: This study was conducted in Outpatient Department of Medicine, Jinnah Hospital, Lahore from 31^st August 2013 to 28^th February 2014.

Materials and Methods: Both male and female with age ranging from 30-60 years having type 2 diabetes for more than 5 years duration were included. Two hundred and sixty diagnosed diabetes patients presenting to outpatient department were enrolled. Screening was done for NAFLD on the basis of ultrasonography. Sampling for HbA1C and lipid profile was done. Data was analyzed using SPSS 17.

Results: Proportion of NAFLD was quite high i.e. 70%. Seventy five patients (28.8%) had abnormal triglyceride level and 72 patients (27.7%) had raised serum cholesterol. Low density lipoprotein was abnormally high in all individuals and high density lipoprotein was low in all individuals. One hundred and six (40.8%) diabetics patients had good control while rest has poor control and 135 patients (51.1%) were obese.

Conclusion:  Proportion of NAFLD was quite high in diabetic patients. We should screen every patient for NAFLD as it may reduce the co morbidity.