Caudal Bupivacaine Alone Versus Bupivacaine with Ketamine to Compare Postoperative Analgesia

Abstract

Objective: To compare the effectiveness of caudal bupivacaine alone and bupivacaine with ketamine in terms of duration of analgesia.

Study Design: Randomized controlled trial study

Place and Duration of study: This study was conducted at the Department Anaesthesia Bakhtawar Amin Hospital, Nishtar hospital, and Children Hospital Multan from May 2017 to May 2018.

Materials and Methods: Study was started after approval from local ethical committee a parental consent was obtained after complete information of study. Main outcome variables are duration of analgesia, pain score, and Bromage score. Data analysis was done with SPSS version 23.1. P value ≤0.05 was taken as statistically significant.

Results: The mean duration of analgesia and time taken to void urine after surgery of the Group A was 5.80±2.71 hours and 4.45±0.51 hours, respectively. While, the mean duration of analgesia and time taken to void urine after surgery of the Group B was 12.53±2.51 hours and 4.52±0.53 hours, respectively.Statistically significant was observed in duration of analgesia. P value 0.000.

Conclusion: Combination of Ketamine 0.5 mg/kg and bupivacaine 0.25% in a dose of 1 ml/kg prolonged the duration of postoperative analgesia toa significant range in comparison with bupivacaine 25% of 1 ml/kg alone.