The Impact of Seminal Zinc on Sperm Morphology in Infertile Pakistani Patients

Abstract

Objective: The present study was designed to assess the impact of seminal Zinc on sperm morphological abnormalities in infertile patients.

Study Design: Descriptive analytical study

Place and Duration of Study: This study was conducted at the Department of Reproductive physiology/Health, Public Health Laboratories Division, National Institute of Health, Islamabad and compiled in the Department of Biochemistry, Bannu Medical College, Bannu from March 2016 to March 2017.

Materials and Methods: Total 1181 subjects were included in the study, out of which 353, 535, 159, 37 were oligozoospermic, asthenozoospermic, oligoasthenozoospermic, teratozoospermic, along 97 proven fathers as control.

Results: The results of the study showed that seminal zinc was 598.48 ± 12.95, 617.54± 9.55, 542.29± 22.75, 710.36± 7.87, and 762.06± 8.99 in oligozoospermic, asthenozoospermic, oligoasthenozoospermic, teratozoospermic, and proven fathers groups respectively, while, head, neck & tail defects in these groups were 26.420.97, 6.640.41 & 6.600.35, 23.400.86,  .4.860.29, & 8.890.49, 31.691.47, 10.820.73 & 8.490.62, 75.432.99, 4.320.89 & 10.081.39, 11.320.87, 1.920.23, & 4.240.62 respectively, showing significant (p<0.05) decline trend in seminal Zinc level whenever, the overall sperm abnormalities gets increased. Out of sperm abnormalities among these groups, the head abnormalities are more prominent as compared to neck & tail defects

Conclusion: It is concluded, that decrease level of seminal Zinc, not only causes hypogonadism, and arrest of spermatogenesis, but also affect the quality and quantity of sperms, and ultimately leads to male infertility.