Frequency of Pregnancy Following Laparoscopic Ovarian Drilling in Patients with Clomiphene Resistant Polycystic Ovarian Syndrome

Abstract

Objective: To determine the frequency of pregnancy following laparoscopic ovarian drilling in patients with clomiphene citrate resistant polycystic ovarian syndrome.

Study Design: Retrospective / Observational study

Place and Duration of Study: This study was carried out in the Department of Obstetrics and Gynaecology DG Khan Medical College, Dera Ghazi Khan from November 2012 to May 2013.

Patients and Methods: One hundred eligible patients who suffer from anovulatory infertility and who failed to respond to the treatment with clomiphene citrate were enrolled from outpatient department

Results: Overall frequency of PCOS was 4.84%. Majority of cases of PCOS were in age group 20-30 years. 72% of cases were having primary infertility and 28% were having secondary infertility. 41.86% of cases were resistant to CC in a dose of 150 mg for three cycles. Conception rate was 66% in 6month follow up period after LOD

Conclusion: Laparoscopic ovarian drilling with diathermy should be considered to be a preferred choice for the infertile women with history of failed response to clomiphene treatment as compared to the use of gonadotrphins.