Evaluation of Serum Triglyceride and Cholesterol in Subclinical Hypothyroidism

Abstract

Objective: This study was aimed to evaluate the effects of subclinical hypothyroidism on lipid profile with special reference to total cholesterol and triglyceride levels.

Study Design: Analytic study

Place and Duration Study: This study was carried out at the Punjab Institute of Nuclear Medicine (PINUM), Faisalabad and IMBB, university of Lahore from January 2011 to September 2011. (Eight months) 

Materials and Methods: 100 female patients of age ranges from 20-50 years having subclinical hypothyroidism (SCH) and 20 euthyroidsubject  of same age and sex (control) were included in this study. Serum FT₄, FT₃, TSH, total cholesterol and triglyceride of subclinical hypothyroid patients and control group were determined.

Result: In subclinical hypothyroid patients total cholesterol were significantly increased as compared to euthyroid group. Serum TSH and total cholesterol showed positive correlation. Serum triglyceride did not significantly increased in SCH.

Conclusion: The total cholesterol level elevated in SCH. This increases the risk of atherosclerotic coronary artery disease (CAD) in subclinical hypothyroid patients.