Comparison of Glyceral Trinitrate (GTN) Paste Application and Lateral Sphincterotomy in Chronic Anal Fissure Management

Abstract

Objective: Comparison of Glyceral Trinitrate (GTN) Paste Application and Lateral sphincterotomy in chronic Anal fissure management.

Study Design: Observational and Experimental Study

Place and Duration of Study: This study was conducted at the Departments of Surgery and Medicine, Sialkot Medical College, Sialkot from Jan 2019 to Jan 2020.

Materials and Methods: 108 patients of chronic anal fissure treated with gylceral trinitrate application compare with lateral sphincteroromy were included in this study. The history, examination and demographic data was recorded in the designed performa. The informed written consent was priorly taken in every case. The permission of ethical committee was also considered in this study. The data was analyzed for results on SPSS version 10.

Results: The response to GTN paste was maximum in 25-30 age group and minimum at 50-60-year age group. In lateral sphincterotomy response was maximum in 25-30 age group, minimum response was seen in patient group 15- 20 year and 50-60 year (table 1). In male response to GTN paste was maximum (51%) whereas in female maximum response was seen with lateral sphincterotomy (64%) (Table 2).  Response to GTN paste was maximum in poor and middle class and minimum in upper class, whereas response to lateral sphincterotomy was maximum in poor class and minimum in middle class (Table 3).

Conclusion: It was concluded from the study that Glyceral Trinitrate was also maximum effected in lateral sphincterotomy at the age of 25-30 years.