Frequencies of Several Histopathological Varieties of Prostatic Diseases in a Tertiary Care Hospital at Larkana

Abstract

Objective: To evaluate the frequencies of various histopathological patterns of prostatic diseases in a tertiary care hospital in Larkana.

Study Design: Cross-Sectional Observational study

Place and Duration of Study: This study was conducted at the Pathology Department, Chandka Medical College, Larkana from April 2021 to April 2023.

Materials and Methods: This study consisted of prostate tissue samples received in the Department of Pathology either by TURP or prostatic resection. Histopathology was evaluated by an experienced pathologist either as benign or malignant diseases and malignant diseases were subsequently graded as per Gleason Score.

Results: There were a total of 147 cases of prostate specimens received during the study duration. The median age range of patients with both benign and malignant disease was 56-60 years. Among these cases, n=116 (78.9%) were benign majorly diagnosed as benign prostatic diseases among these 11 cases had additional histopathological changes and n=31 (21.0%) was malignant with most patients with malignant disease having a Gleason Score of 7.

Conclusion: Prostate disease prevalence in Pakistan is on the rise, particularly in relatively younger populations, requiring future research and treatment efforts.