Serum Uric Acid in Systemic Hypertension Patients and its association with Systolic and Diastolic Blood Pressure

Abstract

Objective: Evaluating the Serum Uric acid (SUA) in Systemic Hypertension Patients and its association with Systolic (SBP) and Diastolic Blood Pressure (DBP).

Study Design: Cross sectional study

Place and Duration of Study: Department of Medicine, Isra University Hospital from April 2017 – February 2018.

Materials and Methods: A sample of 100 diagnosed cases of essential systemic hypertension and 100 controls were selected according to the inclusion and exclusion criteria. Venepuncture was done to collect 2 ml venous blood. The blood samples were centrifuged. Sera were used for the uric acid estimation. Volunteers were asked to give consent in written. A pre- structure performa was used for data collection. Data was analyzed on statistical software (SPSS v 22.0, IBM, Incorporation, USA) at confidence interval of 95% (P ≤ 0.05).

Results: Mean ± SD age was found 50.32±4.13 and 50.25±4.20 years in control and cases respectively (p=0.95). Male population was predominant in present study. Serum uric acid in control and cases was found as 4.42±1.10 and 5.28±1.04 respectively (P=0.0001). Pearson`s correlation shows positive association of Serum Uric acid with systolic BP (r= 0.575^**, p=0.0001), Diastolic BP (r= 0.561^**, p=0.0001) and Body weight (r= 0.132, p=0.063).

Conclusion: The present study reports raised serum uric acid levels in systemic hypertension. Serum Uric acid shows a definite positive correlation with systolic and diastolic blood pressure.