CT Evaluation of Takayasu Arteritis an Initial Experience at CPEIC, Multan

Abstract

Objective: To identify the Takayasu Arteritis (TA) among teenagers & adults patients of South Punjab (Pakistan).

Study Design: Prospective Study

Place and Duration of Study: This study was conducted at the at radiology department of Chaudry Pervaiz Ellahi Institute of Cardiology, Multan (Pak) for a period of one year from April 2016 to April 2017.

Materials and Methods: All patients underwent color doppler ultrasound study for limb ischemia, reno vascular hypertension and carotid doppler ultrasound for stroke like symptoms followed by CT angiography using Toshiba Aquilon 128 slice CT scan and low-osmolar contrast media. Inclusion criteria to establish diagnosis was based on the American College of Rheumatology criteria. SPSS 20 was used to compile and consolidate the data findings.

Results: A total of 4012 patients were studied from them 56% were females and 44% were males, mean age of these patients were 26.34+5.12 years. Amongst them six patients were diagnosed with the disease (TA) from them(83.3%) patients were females and one was male (16.7%).All the six patients radiologically diagnosed as Takayasu Arteritis were further pathologically and clinically evaluated. Mean C-reactive protein (CRP) was 3.60+2.60mg/L while mean ESR 44.33+29.78mm/hr and mean wall thickness was 4.46+1.86mm.

Conclusion: CT Angiography is a very useful and reliable method of diagnosing Takayasu Arteritis, assessing disease activity and a guide to treatment & follow-up.