Compare the Sublingual and Per Rectal Routes of Misoprostol Administration in Third Stage of Labor in Terms of Average Blood Loss

Abstract

Objective: To compare the sublingual and per rectal routes of misoprostol administration in third stage of labor in terms of average blood loss.

Study Design: Randomized controlled trial study.

Place and Duration of Study: This study was conducted at the in Obstetrics and Gynaecology Department, District Headquarter Hospital, Gujranwala during 23-6-2018 to 24-12-2018.

Materials and Methods: 100 patients were selected form the outpatient/ emergency department of District Headquarter Hospital, Gujranwala. The patients were divided in two groups A and B via lottery method. After the delivery of the baby the group A patients received 400 micro grams of misoprostol sublingually while the group B patients received the same amount of misoprostol via rectal route as suppository. Immediately after cord clamping and division, a kidney dish was firmly placed against perineum to collect the blood.

Results: Mean age of women in this study was 31.61±5.2 in Group-A and 29.94±4.54 years in Group-B. Mean amount of blood loss in Group-A and in Group-B was significantly higher in Group-B women i.e. Group-A: 313.14 vs. Group-B: 412.90, p-value=0.000.

Conclusion: Sublingual route of misoprostol administration in third stage of labor in terms of average blood loss was more effective as compared to per rectal route.