Evaluation of Multi Vessel Disease and its Impact on Reperfusion Success in Patients Undergoing Primary Percutaneous Coronary Intervention for Acute Myocardial Infarction

Abstract

Objective: To investigate the frequency multi vessel disease and its impact on reperfusion success in patients undergoing primary percutaneous coronary intervention for acute myocardial infarction.

Study Design: Cross sectional study

Place and Duration of Study: This study was conducted at the Chaudhary Pervaiz Ellahi Institute of cardiology, Multan from June 2021 to May 2022.

Materials and Methods: Visually estimated stenosis of more than or equal to 50% for left main stem and more than or equal to 70% stenosis for epicardial branches of other major arteries was considered as significant atherosclerosis. Rentrop classification was used for analysis of presence of collateral artery to infarct artery. Extent of coronary vessel involvement and reperfusion success was main outcomes variables of study. SPSS version 23 was used for data analysis. P value ≤0.05 was considered significant statistically.

Results: Three hundred patients with mean age 54.45±10.47 and majority of male 171 (57%) patients were included in this study. Baseline characteristics of single, double and triple vessel were compared. ST segment resolution was achieved in >70% in 51.9% of triple vessel diseased patients after PCI that is small proportion as compared to double vessel 56% and single vessel 67.7%. Difference was statistically significant (p=0.012).

Conclusion: Reperfusion success and ST resolution is directly associated with extent of coronary artery disease. Success rate of PCI is higher in single and double vessel diseased patients and low in triple vessel diseased.