Comparison of Crystalloid Preload Rapid Administration after Induction of Spinal Anesthesia in Women Undergoing Elective Caesarean Section

Abstract

Objective: To compare crystalloid preload with prompt administration post induction of spinal anesthesia in women undergoing elective caesarian section.

Study Design: Randomized controlled trial study

Place and Duration of Study: This study was conducted at the Department of Anesthesia, Jinnah Postgraduate Medical Centre, Karachi from July, 2018 to January, 2019 for a period of six months.

Materials and Methods: One hundred and fifty-four patients underwent elective caesarian section under spinal anesthesia were included and divided into two groups, coload and pre load (Group C and Group P). All patients were given bupivacaine. In group P, patients were injected 15 ml/kg ringer lactates solution for over 20 minutes prior to spinal block whereas in group C patients, ringer lactate was injected over 20 min post CSF tapping. Presence of nausea and vomiting were recorded. Maternal hypotension was assessed.

Results: The mean age in Group P was 36.32±6.68 years and Group C was 34.77±5.61 years. In Group P, nausea was 27.3%, vomiting was 37.7% and hypotension was 64.9%. In Group C nausea was 16.9%, vomiting was 9.1% and hypotension was 42.9%. Vomiting and hypotension were significantly association with two study groups but nausea was not found any significance.

Conclusion: Crystalloid preload observed more nausea, vomiting, and hypotension as compared to patients of coload.