Frequency of Proteinuria in Patients with Older-Onset Diabetes Mellitus Attending Civil Hospital Karachi

Abstract

Objective: To determine the frequency of proteinuria in patients with adult-onset diabetes mellitus.

Study Design: Descriptive study

Place and Duration of Study: This study was conducted at Medical Wards of Civil Hospital Karachi from 1^st November 2010 to 30^th April 2011.

Materials and Methods: In this study 100 patients of adult onset diabetes mellitus were enrolled who were admitted in medical department at Civil Hospital Karachi. The duration of the study was 6 months. Diagnosed all patients with type 2 diabetes mellitus and > 40 years of age were included except for patients with urinary tract infection, haematuria, acute febrile illness, congestive cardiac failure, uncontrolled hypertension. A mid-stream urine sample was collected for the determination of UAE; Macroalbuminuria was tested first if it was found negative then urine was tested for Microalbuminuria.

Results: Out of 100 patients 55% patients had normal Albuminuria (<20 mg/liter) while 45% patients had evidence of increased proteinuria (>20 mg/liter). Out of 45 proteinuric patients, 28(62.2%) patients had evidence of Microalbuminuria (cutoff; 20-200 mg/liter) and 17(37.8%) patients had Macroalbuminuria (cutoff; >200 mg/liter)

Conclusion: The concluded that the frequency of microalbuminuria is higher than macroalbuminuria in type 2 diabetic subjects.