Evaluation of Urea, Creatinine and Total Protein in Iraqi Women with Breast Cancer Patients in Pre- and Postmenopausal

Abstract

Objective: To evaluate the relationship between Iraqi women subjected to breast cancer and their serum levels of urea, creatinine, total protein and body mass index.

Study Design: Descriptive study
Place and Duration of Study: This study was conducted at the Anbar Cancer Center, Iraq from 1st October 2023 to 30th June 2024.

Methods: One hundred women's (60 women's with breast cancer and 40 women healthy) were enrolled. They were divided in to two groups (pre-menopausal and post-menopausal). Concentration of serum urea, creatinine and total protein were determined by enzymatic colorimetric method using Semi-Auto Analyzer instrument (spectrophotometry).

Results: The Urea and creatinine concentrations showed significant differences between the breast cancer patients and healthy controls, while total protein and body mass index did not show a significant difference compared to the control group at premenopausal. At post-menopausal all parameter showed a significant difference compared to the control groups. The parameters were compared based on the body mass index and significant differences were observed compared to the control group in pre- and post-menopausal status.

Conclusion: Renal functions test can be considered as risk factors for women's with breast cancer.