The Relationship Between Vitamin D and Glucose Indices and Lipid Profile in Obese Diabetic Patients

Abstract

Objective: To examine the relationship between vitamin D levels, glycemic control values, and lipid profiles of obese diabetic patients.

Study Design: Descriptive study
Place and Duration of Study: This study was conducted at the College of Nursing, University of Basrah, Iraq from 1st January 2025 to 31st March 2025.

Methods: Ninety males of 60 diabetic patients and 30 healthy controls were enrolled. Serum levels of vitamin D, HbA1c, glucose, and the elements of the lipid profile (total cholesterol, triglycerides, low-density lipoprotein-
cholesterol, high-density lipoprotein-cholesterol, and very low-density lipoprotein-cholesterol) were measured in addition to anthropometric measurements.

Results: The diabetic patients had significantly higher body mass index, Inflammation, immunology, the endocrine system, cardiovascular disease, and dyslipidemia. These are just a few of the numerous areas where vitamin D appears to play a regulatory function. Pearson correlation analysis revealed that the level of vitamin D had a significant negative relation with both HbA1c and glucose concentrations. Non-significant or weak correlations between vitamin D and lipid parameters were, however, found.

Conclusion: The possibility of poor glycemic control in obese diabetics being a factor of deficiency of vitamin D and draw attention to the possible advantages of vitamin D monitoring and supplementation in the treatment of diabetes.