Association Between the Difference in Age, Sex, and the Atherogenic Index of Plasma

Abstract

Objective: This study aimed to examine the association between differences in both age and sex with AIP.

Study Design: Cross-sectional study
Place and Duration of Study: This study was conducted at the Department of Clinical Laboratory Sciences, College of Pharmacy, University of Al-Ameed, Karbala, Iraq, from 28 Aug 2024 to 30 March 2025.

Methods: Eight hundred participants were included, equally divided into two groups: males and females. Total cholesterol (TC), triglyceride (TG), and high-density lipoprotein cholesterol (HDL) were examined by the
colorimetric method, while the Friedewald equation estimated low-density lipoprotein cholesterol (LDL-c). AIP was determined using (log10 TG/HDL-c).

Results: The study reveals that females under 40 years tend to have a more favorable lipid profile, with lower levels of AIP, TC, TG, and LDL-c compared to males of the same age. Above 45years, both females and males have
higher AIP and lipid levels. Among male groups, there are no significant differences between the younger and older groups. There was a statistical difference between the two female groups, with the younger one having a better AIP and lipid profile.

Conclusion: The study shows a significant association between age and sex with AIP among the study population.