Comparative study for the Result of Using Different Topical Agents in Management of Second Degree Burn

Abstract

Objective: To determine the best method for second degree burn treatment that provide rapid healing, prevent infection, comfortability, cost and returning the patient to full productivity during treatment period.
Study Design: Comparative study
Place and Duration of Study: This study was conducted at the outpatient private clinic from 20th January 2025 to 31st March 2025.

Methods: This comparative study was done in outpatient private clinic for patients were complaining from burn. Sixty patients were enrolled. These patients were randomly divided into three groups, each group consist of 20 patients. 1st group was managed by topical antibiotic (silver sulfadiazine), 2nd group by oil based herbal paste (MEBO) and 3rd group by hydrocolloid dressing. The outcome measures we investigated in early follow-up for number of dressing changes, conformability and time from treatment until wound healing. In late follow-up we assessed, scar quality after 4 to 6 months from time of burn and cost of treatment.

Results: The mean of time healing regarding patients treated with silver sulfadiazine and MEBO was 8 days, while it was 5 days for patients treated with hydrocolloid. Treatment with hydrocolloid was comfortable in 15 patients (75%), 5 patients (25%) for patients treated with silver sulfadiazine and in 4 patients (20%) treated with MEBO. Three patients used silver sulfadiazine developed hyperpigmentation.

Conclusion: Hydrocolloid has superior early outcomes as compared with other agents in management of second degree burn.