Multidrug Resistant- Escherichia coli – Use of Plant Extracts as Alternative Treatment in Urinary Tract Infection
Abstract
Objective: To evaluate the in-vitro antibacterial activity of Moringa Oleifera (MO) and Murraya Koenigii (MK) leaf extracts against Multidrug resistant- Escherichia coli.
Study Design: In-vitro experimental study.
Place and Duration of Study: This study was conducted at the Ziauddin University from December 2022 to
May 2023.
Methods: Extraction of MO and MK leaves was done by using rotary evaporator. Antibacterial activity of both the plants was evaluated by using Broth Dilution assay and Agar well diffusion assay.
Results: Concentrations from 7.812 mg/ml to 500mg/ml were made in 10% DMSO for both the extracts. No significant antibacterial activity was observed against MDR-E. coli at any tested concentration.
Conclusion: MO and MK leaf extracts were found to be inactive against MDR-E. coli isolated from urine samples of UTI.




























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